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DYSTHYMIA: What type of disease is this?

Dysthymia: An ancient illness of the soul. Hippocrates used to talk about this subject since more than 2500 years ago. Currently, almost 5% of the world population is affected by this disease. In ancient Greek, it meant bad mood, today is a disease. The current international neuropsychiatric diagnosis defines it as a physiological dysfunction of the humour. It affects more women than men and it tends to manifest mostly on people belonging to low social classes.
A dysthymic patient does not suffer from depression; neither gets blocked, nor gets discouraged, on the contrary, does she or he loose interest on the pleasure of living, remaining immune to the sense of duty and scrupulousness. The 2000 Nobel Prize winner of Medicine, Arvid Carlsson affirms that such humour dysfunction is originated by the lack of dopamine which is the neurotransmitter object of his investigation and also has been previously associated with schizophrenia and later with motor activity disorders (Parkinson’s disease). As well, it influences the capacity of experiencing pleasure. However, there is a treatment for dysthymia called amilsupride which directly acts on the pleasure neurotransmitter and it lasts two years long. The first diagnosis of dysthymia was made by Doctor Hagop S. Akiskal, psychiatric professor and director of the International Mood Centre of the University of San Diego (California), when he treated a patient that was referred to him by one his psychoanalyst’s colleagues who was already treating him. This patient was an active man without any symptoms of depression, and while asleep on the doctor’s chair during his sessions, manifested alterations on the Rem brain waves similar to those patients that suffered from depression. From this point, Doctor Akiskal’s studies began, to achieving the Nobel Prize in the year 2000 by presenting the thesis that defended his theory of dysthymia as a disease that needs to be considered as a personality disorder and has to be treated with medication. Additionally, his thesis explained this disease as a type of humour depression characterized by light symptoms to be considered as chronic normally presented during adulthood. It is an insidious disease that confuses many patients and doctors. In fact, dysthymics do not seem depressed and speak with considerable competency about depression; they are sensitive and show empathy for others. They also have humble emotions and feel for other people. It is like an aristocracy of the suffering; the so called pathologic sadness of the dysthymic is different from the natural sadness because it has neither reason nor path: it is chronic. But, how do we know for certain that people who are slightly difficult in character will not end up being treated with medication as dysthimics are? Doctor Akiskal emphasizes: “Dysthimics patients are as equally healthy as a diabetic person with slightly high levels of glycaemia ”.
Many characteristics of the human personality are distributed in a continuum that goes from health to pathology. We simply intend to identify the characteristics of the disease. On the other hand, from the psychiatric point of view, many great dysthimics were Lucretius, Pascal, Montaigne, Puskin and Baudelaire, so?
 

   
 

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Last modified: 01/02/07